CIPO is generally broken into two groups, primary CIPO and secondary CIPO. We have extensive experience in the diagnosis and management of pseudo-obstruction secondary to a variety of underlying factors and conditions. Conditions which can or do affect the nerves and muscles such as Parkinson’s, Hirschsprung’s Disease and uncontrolled Diabetes. Along with its needed effects, ciprofloxacin (the active ingredient contained in Cipro) may cause some unwanted effects.Although not all of these side effects may occur, if they do occur they may need medical attention. Do you know of a review article? This causes bile to build up in the small intestine and eventually run back into the stomach. If you have problems viewing PDF files, download the latest version of Adobe Reader, For language access assistance, contact the NCATS Public Information Officer, Genetic and Rare Diseases Information Center (GARD) - PO Box 8126, Gaithersburg, MD 20898-8126 - Toll-free: 1-888-205-2311. In severe cases, the symptoms are more chronic and can potentially cause significant life-threatening complications during infancy or early childhood. People with the same disease may not have The bladder may also be affected in some children. We want to hear from you. CIPO can however be caused by a number of conditions and events/surgeries: Connective tissue disorders/diseases such as Ehlers-Danlos Syndrome, Systemic Lupus Erythematosus and Scleroderma. EMG has been rarely reported as a cause of chronic intestinal pseudo-obstruction (CIPO), and its histopathological features are not fully elucidated. Causes In intestinal pseudo-obstruction, the intestine is unable to contract and push food, stool, and air through the digestive tract. In many cases, the cause of CIPO is unknown. The symptoms of intestinal pseudo-obstruction are caused by a problem in how the muscles and nerves in the intestines work. Get the latest research information from NIH: https://www.nih.gov/coronavirus (link is external). Side effects requiring immediate medical attention. Do you have updated information on this disease? Autoimmune and metabolic disorders are also known to be associated with secondary CIPO. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The COVID-19 pandemic continues to impact business before Canada’s Intellectual Property Office. It can lead to fever, pain, nausea, and severe complications. The symptoms of CIP are caused by abnormalities affecting muscle or nerves within the gastrointestinal tract. Other sulfa-containing medications can cause a similar pattern of symptoms. However, when testing is performed, no physical evidence of a blockage is found. In many cases, the root cause is unknown. A variety of medications may be used to treat children with CIPO. Questions sent to GARD may be posted here if the information could be helpful to others. It may be primary or secondary Primary or idiopathic (where the cause is unknown) CIPO occurs by itself. CIPO's social media messages are available in both official languages and will be broadcast as close to simultaneously as possible. Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. We want to hear from you. Problems with nerves, muscles, or interstitial, placeholder for the horizontal scroll slider, Office of Rare Disease Research Facebook Page, Office of Rare Disease Research on Twitter, U.S. Department of Health & Human Services, Caring for Your Patient with a Rare Disease, Preguntas Más Frecuentes Sobre Enfermedades Raras, Como Encontrar un Especialista en su Enfermedad, Consejos Para una Condición no Diagnosticada, Consejos Para Obtener Ayuda Financiera Para Una Enfermedad, Preguntas Más Frecuentes Sobre los Trastornos Cromosómicos, Human Phenotype Ontology … For most diseases, symptoms will vary from person to person. The purpose of this letter is to elucidate on the pathophysiology of a disease that is often considered to be idiopathic. These resources provide more information about this condition or associated symptoms. Chronic intestinal pseudo-obstruction (CIPO) is a rare, severe and disabling disorder of gastrointestinal motility. Severe constipation can cause a lot of rectal / anal evacuation problems, which is not something I know a great deal about, but this could be part of the picture. Hereditary health risks and preexisting conditions may result in slow urine flow in the morning. You must actively protect your trademark by spotting and dissuading any infringement attempts. Before making the diagnosis other conditions with similar symptoms should be ruled out. CIPO can cause severe and chronic pain that is very difficult to treat effectively and can occur repeatedly. Sometimes, bacterial infections and poor absorption of nutrients may occur, resulting in malnutrition. Cipro can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar. 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